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Bipolar Disorder Master Guide

In this section of our website we aim to provide a comprehensive evidence-based education about bipolar disorder. The current text is based on Dr Yanni Malliaris' PhD thesis and it summarises the latest knowledge that we have about bipolar disorder. Under each section you will find relevant scientific literature. You may email us your suggestions about how we can improve our bipolar education section through our contact form or via This e-mail address is being protected from spambots. You need JavaScript enabled to view it . We wish for all our patients to have the best possible evidence-based knowledge about their disorder and to make informed decisions about their treatment.

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1 1. 1 Introduction to Bipolar Disorder (Manic-Depressive Illness) 15131
2 1. 2 Historical Roots in Medicine and Ancient Times 18742
3 1.3 Bipolar Disorders: Contemporary Diagnostic Definitions and a Course-Based Typology 12014
4 1.3.1 Diagnostic (DSM-IV) Criteria for Bipolar Episodes 39471
5 Criteria for a Manic/Hypomanic Episodes 84513
6 Criteria for a Major Depressive Episode 36972
7 Criteria for a Mixed Episode 25174
8 1.3.2 Diagnostic Sub-types of Bipolar Disorder: A Course Based Typology 28489
9 1.4 The Unipolar – Bipolar Distinction, Related Comorbities, and Differential Diagnosis 17029
10 1.4.1 Unipolar Depressive Disorder and Bipolar Depression 16252
11 1.4.2 Schizophrenia and Borderline Personality Disorder 29417
12 1.5 Prevalence and age of onset of Bipolar disorders in the general population 29701
13 1.6 Comorbidities, Burden and Cost, and Mortality of Bipolar Disorder 15313
14 1.7 Aetiology of Bipolar Disorder 14130
15 1.8 Treatment of Bipolar Disorder 13782
16 1.9 Natural Course of Bipolar Disorder 14600

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